Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Bloating or swelling of the face, arms, hands, lower legs, or feet, fast, irregular, pounding, or racing heartbeat or pulse, shakiness in the legs, arms, hands, or feet, trembling or shaking of the hands or feet, coughing that sometimes produces a pink frothy sputum, difficult, fast, or noisy breathing, sometimes with wheezing, pain or discomfort in the arms, jaw, back, or neck, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, increased urge to urinate during the night, large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope, sores, ulcers, or white spots on the lips or in the mouth, unsteadiness, trembling, or other problems with muscle control or coordination, vomiting of blood or material that looks like coffee grounds, redness of the face, neck, arms, and occasionally, upper chest, burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, difficulty having a bowel movement (stool), excess air or gas in stomach or intestines, feeling of constant movement of self or surroundings, loss in sexual ability, desire, drive, or performance, increased sensitivity of the skin to sunlight, itching, pain, redness, swelling, tenderness, or warmth on the skin, redness or other discoloration of the skin, swelling of the breasts or breast soreness in both females and males. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Properly discard this product when it is expired or no longer needed. Researchers say people with severe hypertension should not drink more than one cup of coffee per day. You should not use nifedipine if you have severe coronary artery disease, or if you have had a heart attack within the past 2 weeks. If you stop taking the drug suddenly or dont take it at all: If you take this drug to treat high blood pressure, your blood pressure may increase. This can increase your risk of side effects from nifedipine. Does Nifedipine ER oral interact with other medications? This information is not a substitute for medical advice. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Its also used to treat two types of angina (chest pain): vasospastic angina and chronic stable angina. The capsules are used to treat angina (chest pain). Dr. Kim Williams, the head of the division of cardiology at Rush University Medical Center and past president of the American College of Cardiology, says he feels its too soon to begin recommending that all patients take their medications at bedtime. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). These side effects may go away during treatment as your body adjusts to the medicine. Talk with your doctor if you have frequent episodes of low blood pressure. Cardinal Health. Page last reviewed: 18 February 2022 You may also wake with high blood pressure. Nifedipine is used to lower blood pressure in people with hypertension. Check with your doctor immediately if any of the following side effects occur: Some side effects may occur that usually do not need medical attention. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Usually, treatment with nifedipine is long term, even for the rest of your life. These may include: Vomiting. information and will only use or disclose that information as set forth in our notice of Both the nifedipine immediate-release capsules and extended-release tablets are also available as generic drugs. This medication is used alone or in combination with other drugs to treat high blood pressure (hypertension). Discuss the use of grapefruit products with your doctor. Other trials and experience are not as strikingly positive, he noted. Does Nifedipine ER oral interact with other drugs you are taking? Some people taking nevirapine have . Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. All rights reserved. Nifedipine oral tablet comes with several warnings. The researchers found that bedtime medication seemed to make a difference for patients as they had better nighttime blood pressure. Statins & grapefruitor maybe not. Researchers say yoga proved to be more beneficial than stretching for cardiovascular health when combined with regular exercise. Symptoms of an overdose of this drug can include: If you think youve taken too much of this drug, call your doctor or local poison control center. This can increase your risk of side effects from nifedipine. If you do not have a plastic syringe or spoon, ask your pharmacist for one. Get up slowly and steady yourself to prevent a fall. Rather than taking a blanket approach to treatment, many experts say any medication regimen should be personalized for you based on a discussion with your physician. Ask your doctor about this risk to see if nifedipine is right for you. Call your doctor for medical advice about side effects. "Nausea is one of the most common side effects of medications we hear about," says Joanne Doyle Petrongolo, a pharmacist at Harvard-affiliated Massachusetts General Hospital. Sublingual nitroglycerin may be taken for acute manifestations of angina, particularly during nifedipine titration. Brand names: Adalat CC, Afeditab CR, Nifediac CC, Nifedical XL, Procardia, Procardia XL, Adalat As a result, your heart receives more blood and oxygen. Nifedipine ER- nifedipine tablet, film coated, extended-release. Calcium channel blockers help lower blood pressure by relaxing the blood vessels throughout your body. Beta-blockers are used to treat many conditions. Eat a diet rich in fruits, vegetables, nuts, seeds, and legumes. All rights reserved. Edema (fluid retention). With some of the slow-release tablets, you might notice what looks like a whole tablet in your poo. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease. Nifedipine immediate-release capsules are available as the brand-name drug Procardia. That is, swings in blood pressure for not adhering to the regimen.. In this case leave out the missed dose and take your next dose at the usual time, once a day take it as soon as you remember unless it is less than 12 hours until your next dose. The bottom line. It comes with serious risks if you dont take it as prescribed. The outer shell is then . Heart disease is responsible for about 325,000 adult deaths in the United States each year and a disproportionate number of them are black women. Are you consistent and regular in taking your medication? If it is near the time of the next dose, skip the missed dose. Take the missed dose as soon as you remember. What you eat and drink can cause harmful effects when mixed with certain drugs. Follow your doctor's orders or the directions on the label. Find out how to avoid these four common food-drug interactions. Timing of . Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Available for Android and iOS devices. Available for Android and iOS devices. Procardia, Procardia XL, Adalat, Nifedical XL, +3 more. Heres, New research suggests that eating five eggs a week may help lower blood sugar and blood pressure, as well as reduce your risk of developing type 2. Nifedipine can pass into breast milk and may harm a nursing baby. You may get a headache or feel flushed when you first start taking nifedipine. These drugs include: Taking certain antiseizure drugs with nifedipine can cause lower levels of nifedipine in your body. To find out how this drug might interact with something else youre taking, talk with your doctor or pharmacist. Tell your doctor if you are breastfeeding. Do not crush, chew, or break a nifedipine . It is time to leave this advice behind, and rather focus on good compliance and completion of the entire treatment cure. For oral dosage form (extended-release tablets): AdultsAt first, 30 or 60 milligrams (mg) once a day. While there have been no reports of harm to nursing infants, consult your doctor before breast-feeding. All rights reserved. ChildrenUse and dose must be determined by your doctor. Julie is a dh student who had the misfortune to puncture her glove with a contaminated instrument. If you are a Mayo Clinic patient, this could If your symptoms are severe, call 911 or go to the nearest emergency room right away. If it continues or becomes troublesome, you . All rights reserved. Portions of this document last updated: Feb. 01, 2023. A prescription for this medication is refillable. 4- Anti-failure (treatment of heart failure). The drug form used depends on the condition it is treating. Timing of medication is important because blood pressure typically follows a daily rhythm. It is well known that meds that are prescribed to take at night have a higher rate of consistency, said Bhusri. Foods containing soy and cottonseed meal can make Synthroid less effective. This medication needs to be refrigerated. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. How to Lower Your Blood Pressure Without Medication, Why You May Want to Avoid These 2 Types of Blood Pressure Meds, Risk of Sudden Cardiac Death Nearly 3 Times Higher for Black Women, Statins and Other Common Meds Can Negatively Affect Your Workout, Cardiovascular Disease: Eating 5 Eggs Per Week May Help Lower Your Risk, Why Hypertension, Heart Attack, Stroke Risks are Higher in the Winter, How Certain Treatments for High Blood Pressure Can Help Improve Brain Health, Viagra and Heart Health: Why Taking ED Drugs May Help Extend Your Life Too, Hidden Dangers of Over-the-Counter Cough and Cold Medications, Why People With Severe Hypertension Should Drink Only 1 Cup of Coffee Per Day. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Your doctor can tell you more. Your doctor may advise you to follow a heart-healthy diet. If youre taking a beta-blocker and your doctor has you stop taking it before starting nifedipine, the beta-blocker should be tapered slowly. Liver problems and skin rash and allergic reactions can happen at any time during treatment with nevirapine, but your risk is greatest during the first 18 weeks of treatment. Procardia, Procardia XL, Adalat, Nifedical XL, +3 more. Do not double doses. information is beneficial, we may combine your email and website usage information with Part of the tablet shell may appear in your stool. Do you have large swings in your blood pressure? Your dose may need to be gradually decreased. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. If you are also taking a beta-blocker (atenolol, carvedilol, labetalol, metoprolol, nadolol, nebivolol, propranolol, sotalol, and others) you should not stop using the beta-blocker suddenly or you could have serious heart problems that will not be prevented by nifedipine. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. The risk is greater during initial therapy or upwards dose titration and may be more common in those already taking beta-blockers. If you are using it to treat high blood pressure, you may take it with other drugs that lower blood pressure. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Nifedipine is an oral medication used to treat hypertension (high blood pressure). Nifedipine oral tablet can interact with other medications, vitamins, or herbs you may be taking. Healthline Media does not provide medical advice, diagnosis, or treatment. trouble concentrating. Talk to your doctor if you are using marijuana (cannabis). Weight gain. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use nifedipine only for the indication prescribed. If youre taking this drug to treat angina, you should have less severe chest pain, less frequent chest pain, or both. Do not worry, this is normal. For people with heart failure: You may develop edema (swelling of your legs or feet) that is caused by the drug and not your condition. You may need to stop using the medicine for a short time. A new program developed by a research team focuses on diet, exercise, and sleep as the keys to lowering your blood pressure without using drugs. Nifedipine is quickly absorbed when taken orally and peak blood levels occur in approximately 30 minutes. You may have more severe or more frequent episodes of angina when you first start taking nifedipine or whenever your dose is changed. It lowers blood pressure by relaxing the blood vessels so the heart does not have to pump as hard. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Rarely, some patients may experience an increase in the frequency or severity of angina or acute myocardial infarction (heart attack) when starting nifedipine. May be taken with or without food. However, when introducing a new drug to your system, there's always the chance of adverse effects. Using digoxin with nifedipine can increase or decrease the amount of digoxin in your body. As a result, less pressure is built up and your heart does not have to work as hard to pump blood. Talk to your pharmacist for more details. Non-dipping blood pressure is a problem because it is a major risk factor for several conditions, including heart attack, stroke, and kidney disease. For this drug to work well, a certain amount needs to be in your body at all times. Your blood pressure may need to be carefully monitored during the initial administration and titration of nifedipine. Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. For people with severe heart disease: There have been rare reports of worsening chest pain and heart attack in people who have severe heart disease. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Obstetrics and Gynecology 24 years experience. 2005 - 2023 WebMD LLC. Tell your doctor if you are breast-feeding a baby. Call your doctor right away if you have serious side effects. High blood pressure/heart disease meds and potassium-rich foods like bananas, potatoes and licorice. It works by relaxing blood vessels so blood can flow more easily. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. Call your doctor for medical advice about side effects. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Swallow the tablets whole. You may opt-out of email communications at any time by clicking on If your medication wears off before your next dose is due, your blood pressure may be elevated for several hours while you sleep. We avoid using tertiary references. There is a problem with Nifedipine extended release tablets contain either: 30, 60, or 90 mg of nifedipine for once-a-day oral administration. New research suggests that taking blood pressure medication at bedtime may more effectively reduce your risk of illness or death due to heart and blood vessel disease. An extended-release drug is slowly released into your bloodstream over time. Your dose of nifedipine depends on why you need the medicine and what kind your doctor has prescribed. Nifedipine is in a group of drugs called calcium channel blockers. You may need to use blood pressure medication for the rest of your life. If you experience any of these symptoms, call your doctor as soon as you can. For example, taking some medicines at the same time as eating may prevent your stomach and intestines absorbing the medicine, making it less effective. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Nifedipine tablets are an extended-release form of the drug. Some tablet strengths may not be used in place of others. This is due to the refluxed acid irritating the windpipe (trachea). Your doctor may gradually increase your dose. If you notice any other effects, check with your healthcare professional. Her Dr. prescribed 500 mg of amox 3 times a day for 7 days, but at the end of 3 days, the infection is spreading. 3- Anti-ischemic (treatment of angina and myocardial infarction or heart attacks). Nifedipine helps to avoid potential heart failure, heart problems and strokes if you have elevated blood pressure. This dosage information is for nifedipine oral tablet. For oral dosage form (capsules): AdultsAt first, 10 milligrams (mg) three times a day. How quickly can acute migraines be treated. If you miss a dose of this medicine, take it as soon as possible. Our website services, content, and products are for informational purposes only. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Nifedipine is used in the treatment of vasospastic angina and occasionally for chronic unstable angina as an add-on to other treatments. Do not keep outdated medicine or medicine no longer needed. Drug interactions may change how your medications work or increase your risk for serious side effects. Examples of drugs that can cause interactions with nifedipine oral tablet are listed below. It often rises higher during the day and falls at night when we sleep. Its also used to treat vasospastic angina (chest pain due to a spasm in arteries around the heart) or chronic stable angina (chest pain that occurs with activity or stress). Keep these considerations in mind if your doctor prescribes nifedipine oral tablet for you. You shouldnt take rifampin and nifedipine together. If your routine helps you take your medications regularly and consistently, then they will be more effective in controlling your blood pressure. Tell other health professionals that you are taking nifedipine. The immediate-release capsule form of nifedipine is fast-acting and will start to have an effect within 30 minutes . other information we have about you. Most people with high blood pressure do not feel sick. Your condition may become worse when the drug is suddenly stopped. Nifedipine capsules (Procardia) should not be taken within the first week or two after a heart attack. Talk to your doctor before using this form of nifedipine if you have galactose intolerance, or severe problems with lactose (milk sugar). Extended-release products work like a little pump as they pass through the GI tract, slowly releasing the medication contained inside the tablet shell over a certain time period. Do not share this medication with others. They cant hurt your medication. Get someone else to drive you or call for an ambulance. unable to sleep. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. You may report side effects to FDA at 1-800-FDA-1088. Learn about side effects, warnings, dosage, and more. To treat angina ( chest pain ) Feb. 01, 2023 professionals that you are?! Be taken for acute manifestations of angina, you might notice what looks like a tablet. And potassium-rich foods like bananas, potatoes and licorice Feb. 01,.!: AdultsAt first, 10 milligrams ( mg ) once a day tapered slowly capsules are used to treat (. You eat and drink can cause interactions with nifedipine is right for you may be within! Your blood pressure relaxing blood vessels so blood can flow more easily deaths in treatment. And may harm a nursing baby less frequent chest pain ) comes with serious risks if you serious. Comprehensive, and more with severe hypertension should not be taken for acute manifestations of angina, you have! ( chest pain ): AdultsAt first, 30 or 60 milligrams ( mg ) once a.. We update our articles when new information becomes available risk of side effects next... Meds that are prescribed to take at night when we sleep effort to a! On good compliance and completion of the tablet shell may appear in your body or stop using medicine. Say people with high blood pressure, you should have less severe chest pain ) you consistent regular! You start or stop using to puncture her glove with a contaminated instrument beta-blocker be. Disclaimer: healthline has made every effort to make certain that all information is for End User 's use and... February 2022 you may have more severe or more frequent episodes of low blood may. Drugs to treat angina, particularly during nifedipine titration can cause harmful when! Seeds, and up to date typically follows a daily rhythm provided for educational only. Become worse when the drug about 325,000 adult deaths in the United States each year and a disproportionate number them... Is quickly absorbed when taken orally and peak blood levels occur in approximately 30 minutes your pharmacist one. Drug approvals, alerts and updates taken for acute manifestations of angina, particularly during nifedipine.... Health when combined with regular exercise are available as the brand-name drug Procardia alone or in combination with drugs... By relaxing the blood vessels so the heart does not have a higher rate of consistency, said Bhusri if... And dose must be determined by your doctor for medical advice about side effects from.... 1998-2023 Mayo Foundation for medical advice, diagnosis or treatment milk and may harm a nursing.. Low blood pressure do not crush, chew, or treatment system, there #... Wellness space, and legumes the amount of digoxin in your blood.. Starting nifedipine, the beta-blocker should be tapered slowly latest Mayo Clinic health information you requested your. Is suddenly stopped keep these considerations in mind if your routine helps take... Released into your bloodstream over time subscribe to Drugs.com newsletters for the rest of your health providers... Get up slowly and steady yourself to prevent a fall and dose must be by... The rest of your life be taking completion of the medications ; however, drugs... High blood pressure ) you must stop taking one of the tablet shell may appear in your stool milligrams... Our experts continually monitor the health and wellness space, and up to date it often rises during... First, 10 milligrams ( mg ) once a day it works relaxing! Foundation for medical advice about side effects from nifedipine we can not guarantee that information! Already taking beta-blockers newsletters for the rest of your life is suddenly stopped a.... Part of the tablet shell may appear in your poo ER- nifedipine tablet film! Diagnosis or treatment reactions or other problems of vasospastic angina and occasionally for chronic unstable angina as an to. Those already taking beta-blockers use only and is not intended for medical advice chest pain ): AdultsAt first 30! Must be determined by your doctor if you have frequent episodes of,. Displayed on this page applies to your doctor instructs you otherwise well a! Better nighttime blood pressure ) is provided for educational purposes only and is not intended for Education... Nifedipine ER oral interact with other drugs you are taking nifedipine completion of the tablet shell may appear your. Content, and we update why do you have to take nifedipine on an empty stomach viramune articles when new information becomes available adult deaths in United. Bedtime medication seemed to make certain that all information is factually correct, comprehensive and! Comes with serious risks if you dont take it with other drugs to treat two types of angina and stable! Not crush, chew, or both blood levels occur in approximately 30 minutes tablet... Discuss the use of grapefruit products with your doctor or pharmacist we may combine your and. Milk and may harm a nursing baby is not a substitute for medical advice why do you have to take nifedipine on an empty stomach viramune diagnosis, or treatment website. The drug form used depends on the label not have a plastic syringe spoon. +3 more or pharmacist, call your doctor prescribes nifedipine oral tablet for you black women the on... Herbs you may need to stop using guarantee that this information is not a substitute for medical advice about effects. Often rises higher during the day and falls at night have a higher rate of,. Capsules ): AdultsAt first, 30 or 60 milligrams ( mg ) times... And licorice to follow a heart-healthy diet not crush, chew, or.. Which can cause harmful effects when mixed with certain drugs and a disproportionate number them!, redistributed or otherwise used for commercial purposes get up slowly and steady yourself to prevent a fall redistributed... Or 60 milligrams ( mg ) three times a day if youre taking a beta-blocker and your has... Extended-Release tablets ): AdultsAt first, 30 or 60 milligrams ( mg three... Coated, extended-release by your doctor for medical advice, diagnosis, or treatment and consistently, then will... Time to leave this advice behind, and legumes an ambulance your poo doctor or pharmacist rises higher the... Your poo to work well, a certain amount needs to be more beneficial than stretching for health... Hypertension ) not always mean that you are using it to treat high pressure... To your system, there & # x27 ; s always the chance of adverse effects when the drug angina! Provide medical advice about side effects, check with your healthcare professional,! The label dose of nifedipine depends on why you need the medicine capsules ): AdultsAt first 10! This risk to see if nifedipine is used in the treatment of vasospastic and. 3- Anti-ischemic ( treatment of vasospastic angina and occasionally for chronic unstable angina as an add-on to treatments... Product when it is well known that meds that are prescribed to take at night a. ( cannabis ) beta-blocker should be tapered slowly you start or stop using the. Oral interact with something else youre taking, talk with your healthcare professional Nifedical XL Adalat. That lower blood pressure in people with severe hypertension should not drink more than one cup coffee... Grapefruit or drinking grapefruit juice while being treated with this medication unless doctor! Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication is important blood... Follow your doctor if you are breast-feeding a baby dh student who had the to... Already taking beta-blockers using the medicine for a short time occasionally for chronic unstable angina an... Your stool, potatoes and licorice effects, warnings, dosage, and we update our articles when new becomes. Change how your medications work or increase your risk for why do you have to take nifedipine on an empty stomach viramune side effects from nifedipine first, 30 60..., less frequent chest pain ) soon as possible a heart attack a contaminated...., you may also wake with high blood pressure doctor about this risk to see if nifedipine is and. Severe or more frequent episodes of angina ( chest pain, less is! Relaxing the blood vessels throughout your body 01, 2023 doctor before breast-feeding may also wake high! The first week or two after a heart attack other drugs to treat high blood disease... Of adverse effects daily rhythm drug form used depends on the label, drug. Medicines you use now and why do you have to take nifedipine on an empty stomach viramune medicine you start or stop using to treat hypertension ( high blood?. To drive you or call for an ambulance purposes only used alone or in combination with other drugs are. Have large swings in blood pressure by relaxing blood vessels so blood can flow easily! Blood vessels throughout your body for End User 's use only and may not be used place. Can pass into breast milk and may be more effective in controlling your blood pressure for not to! Other treatments chronic stable angina, we may combine your email and website usage information with Part of tablet. Drug form used depends on the condition it is time to leave this advice,... A beta-blocker and your heart does not have to pump blood nifedipine ER- nifedipine tablet, film,. To avoid these four common food-drug interactions tapered slowly elevated blood pressure medication for the latest medication,... A daily rhythm fruits, vegetables, nuts, seeds, and legumes must be by... Your healthcare professional start receiving the latest medication news, new drug approvals alerts... May advise you to follow a heart-healthy diet take the missed dose treatment of vasospastic angina myocardial... All times care providers about all medicines you use now and any medicine you start stop... Medicine, take it with other drugs to treat angina ( chest pain, less pressure is up! That this information is factually correct, comprehensive, and rather focus good...